glutamate into the synaptic cleft. This video is an
excerpt from an academic presentation for current
research on Huntington Disease (HD).
about huntington’s disease
Huntington’s Disease is a fatal progressive neurodegenerative disorder. One proposed
cellular mechanism underlying neuron degeneration is excitotoxic pathways mediated
by glutamate receptors. Overstimulation of these receptors due to their enhanced
responsiveness, or increased release or decreased uptake of glutamate, can result
in neuronal stress or death via the excessive influx of water an ions, especially
calcium. Read related article.
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