Description
This excerpt is taken from our 3D animation work for a biopharmaceutical company that developed an FDA-approved orphan drug, aimed at treating the rare genetic disease homozygous familial hypercholesterolemia (HoFH).
This video explores the activity within the body of a person affected with HoFH; explaining the normal and abnormal functions of LDL-C.
Deliverables
3D animations, multiple language videos, 3D illustrations - online, banner & brochure
Brand
Juxtapid (USA) & Lojuxta (EU)
Client
Aegerion Pharmaceuticals
Aegerion Pharmaceuticals
Massachusetts, USA
What Is Homozygous Familial Hypercholesterolemia (HoFH)
1Familial hypercholesterolemia (FH), an autosomal codominant disease, is characterized by high levels of LDL cholesterol and a high incidence of coronary artery disease (CAD).
2Homozygous Familial Hypercholesterolemia, or HoFH, is a rare genetic lipid disorder usually caused by defects in the low-density lipoprotein, or LDL, receptor genes, inherited from both parents, resulting in impaired or total loss of function in the LDL receptor.
references: 1www.circ.ahajournals.org Article: Coronary Artery Disease in Heterozygous Familial Hypercholesterolemia Patients With the Same LDL Receptor Gene Mutation / J. Ferrieres, MD, MSc; J. Lambert, PhD; S. Lussier-Cacan, PhD; J. Davignon, MD, Msc,
2aegerion.com