This medical animation shows that during the course of tumor progression, cancer
cells acquire a number of characteristic alterations.
about tumor cell signalling
Cancer cells characteristic alterations include the capacities to proliferate independently
of exogenous growth-promoting or growth-inhibitory signals, to invade surrounding
tissues and metastasize to distant sites, to elicit an angiogenic response, and to
evade mechanisms that limit cell proliferation, such as apoptosis and replicative
senescence. These properties reflect alterations in the cellular signalling pathways
that in normal cells control cell proliferation, motility, and survival.