medical animation

The visual science of a first-in-class treatment in HoFH.


This excerpt is taken from our 3D animation work for a biopharmaceutical company that developed an FDA-approved orphan drug, aimed at treating the rare genetic disease homozygous familial hypercholesterolemia (HoFH).

This video explores the activity within the body of a person affected with HoFH; explaining the normal and abnormal functions of LDL-C.


3D animations, multiple language videos, 3D illustrations - online, banner & brochure


Juxtapid (USA) & Lojuxta (EU)


Aegerion Pharmaceuticals

Familial Hypercholesterolemia (HoFH) Animation

It has been great working with you and we really appreciate all your work to make the videos become a reality.

Aegerion Pharmaceuticals
Massachusetts, USA

What Is Homozygous Familial Hypercholesterolemia (HoFH)

1Familial hypercholesterolemia (FH), an autosomal codominant disease, is characterized by high levels of LDL cholesterol and a high incidence of coronary artery disease (CAD).

2Homozygous Familial Hypercholesterolemia, or HoFH, is a rare genetic lipid disorder usually caused by defects in the low-density lipoprotein, or LDL, receptor genes, inherited from both parents, resulting in impaired or total loss of function in the LDL receptor.

references: 1www.circ.ahajournals.org Article: Coronary Artery Disease in Heterozygous Familial Hypercholesterolemia Patients With the Same LDL Receptor Gene Mutation / J. Ferrieres, MD, MSc; J. Lambert, PhD; S. Lussier-Cacan, PhD; J. Davignon, MD, Msc,


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